Activation of autophagy inhibits NLRP3 inflammasome activation and attenuates myocardial ischemia ‐reperfusion injury in diabetic rats

ConclusionActivation of autophagy can suppress the NLRP3 inflammasome formation, which in turn attenuates myocardial ischemia reperfusion injury in diabetic rats.

Source: Journal of Diabetes Investigation - February 17, 2020 Category: Endocrinology Authors: Dengwen Zhang, Yi He, Xiaodong Ye, Yin Cai, Jindong Xu, Liangqing Zhang, Mingyi Li, Hao Liu, Sheng Wang, Zhengyuan Xia Tags: ORIGINAL ARTICLE Source Type: research