[Determination of the Subspecies of Francisella tularensis Isolated in Turkey by Molecular Methods].

[Determination of the Subspecies of Francisella tularensis Isolated in Turkey by Molecular Methods].
Mikrobiyol Bul. 2020 Jan;54(1):1-10
Authors: Çelebi B, Bakkaloğlu Z, Ünaldı Ö, Karagöz A, Kılıç S, Durmaz R
Abstract
Francisella tularensis is a gram-negative, coccobasillus, facultative intracellular bacteria and causes a zoonotic disease, tularemia in humans. F.tularensis has four subspecies, which have different virulences for humans as F.tularensis subsp. tularensis, F.tularensis subsp. holarctica, F.tularensis subsp. mediasiatica and F.tularensis subsp. novicida. F.tularensis subsp. tularensis is the most virulent subspecies and mortality rate is high in human cases. F.tularensis subsp. holarctica, which has been reported in our country to date, has lower virulence than that of subsp. tularensis, and causes rare lethality among untreated patients. According to the erythromycin resistance and the properties of glucose-glycerol fermentation, F.tularensis subsp. holarctica has three biovar as biovar I, biovar II and biovar japonica. F.tularensis subsp. mediasiatica has been reported only in a few central asian countries and its virulence is similar to the F.tularensis subsp. holarctica F.tularensis subsp. novicida is avirulent for immunocompetent individuals but has been observed to cause infection in immunocompromised individuals. The aim of this study was to determine the F.tularensis subspecies in 259 F.tularensis strain...

Source: Mikrobiyoloji Bulteni - February 14, 2020 Category: Microbiology Tags: Mikrobiyol Bul Source Type: research