Lignans from medicinal plants and their anticancer effect.

Lignans from medicinal plants and their anticancer effect.
Mini Rev Med Chem. 2020 Feb 11;:
Authors: Teodor ED, Moroeanu V, Radu GL
Abstract
Since early times, various plants have been used as remedies for treating different kinds of diseases and lesions with satisfying results. The phenolic compounds are secondary metabolites from medicinal plants which include a wide category of compounds such as phenolic acids, flavonoids, tannins, stilbenes, curcuminoids, xanthones, coumarins, lignans, etc. Between these, lignans are considered important in cancer prevention and treatment, besides others beneficial health effects, e.g. antioxidant, anticarcinogenic, antimutagenic and anti-estrogenic effects. This review summarizes the most recent literature and the most important results concerning plant lignans and their derivatives in cancer prevention and treatment, both in vitro and in vivo assessments. The mechanistic aspects will be also highlighted.
PMID: 32048969 [PubMed - as supplied by publisher]

Source: Mini Reviews in Medicinal Chemistry - February 10, 2020 Category: Chemistry Authors: Teodor ED, Moroeanu V, Radu GL Tags: Mini Rev Med Chem Source Type: research