Exhaled air analysis as a potential fast method for early diagnosis of dengue disease

In this study, we report for the first time the possibility of identification of possible biomarkers associated with dengue disease in the exhaled air, and of the development of a breath test for fast, non-invasive and easy diagnosis of this disease. Further, we demonstrate a new deployable sensor technology based on a chemoresistive metal-ligand nanoassembly tailored for the identified possible biomarkers of dengue disease, which achieved 100% accuracy for dengue diagnosis on our study group and can be used in both specialist and non-specialist settings. Nevertheless, as the present study was performed on a limited number of patients because of the difficulty to recruit a high number of patients because dengue is a neglected disease, future validation tests on a higher cohort are necessary for corroborating the results obtained in the present study.
Source: Sensors and Actuators B: Chemical - Category: Chemistry Source Type: research