Cognitive function in Down's syndrome restored in mouse model

A selective GABA inverse agonist has restored cognitive function in a mouse model of Down's syndrome (DS) and has the potential to benefit humans, French researchers have revealed. "The drug we used is a specific GABA-A Î±5 inverse agonist (Î±5IA) that hypothetically could combat the abnormal neuronal excitation/inhibition balance associated with DS", explained lead researcher Dr Benoit Delatour from the Research Centre of the Institute of Brain and Spinal Cord (Centre de Recherche de l'Institut du Cerveau et de Moelle EpiniÃ¨re) at the University Pierre and Marie Curie, Paris...

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Source: Health News from Medical News Today - October 9, 2013 Category: Consumer Health News Tags: Pediatrics / Children's Health Source Type: news