A novel, yet simple MLC-based 3D-crossfire technique for spatially fractionated GRID therapy treatment of deep-seated bulky tumors.

CONCLUSION: The simple MLC-based 3D-crossfire GRID-therapy technique resulted in enhanced target coverage for de-bulking deep-seated bulky tumors, reduced skin toxicity and spare adjacent critical structures. This simple MLC-based approach can be easily adopted by any radiotherapy center. It provides detailed dosimetry and a safe and effective treatment by eliminating the heavy physical GRID-block and could potentially provide same day treatment. Prospective clinical trial with higher tumor-dose to bulky deep-seated tumors is anticipated.
PMID: 32034989 [PubMed - as supplied by publisher]

Source: Journal of Applied Clinical Medical Physics - February 7, 2020 Category: Physics Authors: Pokhrel D, Halfman M, Sanford L, Chen Q, Kudrimoti M Tags: J Appl Clin Med Phys Source Type: research