SERT and BDNF polymorphisms interplay on neuroticism in borderline personality disorder

Genetic factors underlying different personality traits are not entirely understood, particularly how genes interact to modulate their effect. We studied 76 patients diagnosed with borderline personality disor...
Source: BMC Research Notes - Category: Research Authors: Tags: Research note Source Type: research

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AbstractResearch on psychotherapies for posttraumatic stress disorder (PTSD) is increasingly focused on understanding not only which treatments work but why and for whom they work. The present pilot study evaluated the temporal relations between five hypothesized change targets —posttraumatic cognitions, guilt, shame, general emotion dysregulation, and experiential avoidance—and PTSD severity among women with PTSD, borderline personality disorder, and recent suicidal and/or self‐injurious behaviors. Participants (N = 26) were randomized to receive 1 year of dialectical behavior therapy (DBT) with or without t...
Source: Journal of Traumatic Stress - Category: Psychiatry & Psychology Authors: Tags: BRIEF REPORT Source Type: research
INTRODUCTION: High levels of impulsivity represent a core feature of various psychiatric conditions, such as Attention Deficit Hyperactivity Disorder (ADHD), Borderline Personality Disorder (BPD), Impulse Control and Conduct Disorders, Bulimia Nervosa, Sub...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news
CONCLUSIONS: Patient characteristics influence the degree to which they respond to two treatments for BPD. Combining information from multiple moderators may help inform providers and patients as to which treatment is the most likely to lead to long-term symptom relief. Further research on personalized medicine in BPD is needed. PMID: 32204742 [PubMed - as supplied by publisher]
Source: Psychological Medicine - Category: Psychiatry Authors: Tags: Psychol Med Source Type: research
BACKGROUND: Bipolar disorder and borderline personality disorder (BPD) are each significant public health problems. It has been frequently noted that distinguishing BPD from bipolar disorder is challenging. Consequently, reviews and commentaries have focus...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news
Journal of Personality Disorders,Volume 34, Issue Supplement, Page 6-24, March 2020.
Source: Journal of Personality Disorders - Category: Psychiatry Authors: Source Type: research
Although great advancements in evidence-based therapies, chronic suicidal patients with borderline personality disorder (BPD) still challenge our mental health system. While BPD patients continue suffering from distress and aversive emotions, therapists and relatives feel often stunned and helpless when confronted with suicidality resulting in interruption of therapies, repeated presentations to emergency rooms and referrals to hospitals. Reviewing the current knowledge of the functions and background of non-suicidal self-injury, we learned that reinforcement mechanisms play an important role to understand why individuals ...
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
OBJECTIVE: Suicide remains a leading cause of death in the United States, and recent reports have suggested the suicide rate is increasing. One of the most robust predictors of future suicidal behavior is a history of attempting suicide. Despite this, litt...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Research Methods, Surveillance and Codes, Models Source Type: news
Publication date: Available online 16 March 2020Source: Journal of Contextual Behavioral ScienceAuthor(s): Julia R. Richmond, Matthew T. Tull, Kim L. Gratz
Source: Journal of Contextual Behavioral Science - Category: Psychiatry & Psychology Source Type: research
CONCLUSIONS: Patients with both bipolar disorder and BPD have more severe psychosocial morbidity than patients with only one of these disorders. PMID: 32178744 [PubMed - as supplied by publisher]
Source: Psychological Medicine - Category: Psychiatry Authors: Tags: Psychol Med Source Type: research
Conditions:   Treatment 1:Dialectical Behavior Therapy (DBT);   Treatment 2:Dynamic Deconstructive Psychotherapy (DDP);   Placebo Interventions:   Behavioral: DBT;   Behavioral: DDP;   Other: control group Sponsor:   Shalvata Mental Health Center Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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