Endometrioma, the follicular fluid inflammatory network and its association with oocyte and embryo characteristics

ConclusionsThe results suggest that the inflammatory milieu of ovarian endometriosis is strongly localized and has a more modestly systemic effect. The effect of endometriomas on infertility, however, cannot be entirely explained by increased inflammation.
Source: Reproductive BioMedicine Online - Category: Reproduction Medicine Source Type: research

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Shabnam Bhandari Grover, Neha Antil, Amit Katyan, Heena Rajani, Hemal Grover, Pratima Mittal, Sudha PrasadIndian Journal of Radiology and Imaging 2020 30(1):32-45 Infertility is a major social and clinical problem affecting 13–15% of couples worldwide. The pelvic causes of female infertility are categorized as ovarian disorders, tubal, peritubal disorders, and uterine disorders. Appropriate selection of an imaging modality is essential to accurately diagnose the aetiology of infertlity, since the imaging diagnosis directs the appropriate treatment to be instituted. Imaging evaluation begins with hystero- salping...
Source: Indian Journal of Radiology and Imaging - Category: Radiology Authors: Source Type: research
ConclusionEndometrioma stripping followed by the application of a polysaccharide agent could avoid ovarian failure and at same time could reduce adhesion formation, thereby preserving tubo-ovarian function in endometrioma surgery. We encourage other surgically working groups to investigate middle- and long-term effects of this combined technique.
Source: Archives of Gynecology and Obstetrics - Category: OBGYN Source Type: research
CONCLUSIONS: We found no evidence on the effects of barrier agents used during pelvic surgery on pelvic pain or live birth rate in women of reproductive age because no trial reported these outcomes. It is difficult to draw credible conclusions due to lack of evidence and the low quality of included studies. Given this caveat, low-quality evidence suggests that collagen membrane with polyethylene glycol plus glycerol may be more effective than no treatment in reducing the incidence of adhesion formation following pelvic surgery. Low-quality evidence also shows that oxidised regenerated cellulose may reduce the incidence of ...
Source: Cochrane Database of Systematic Reviews - Category: General Medicine Authors: Tags: Cochrane Database Syst Rev Source Type: research
AbstractIntroductionOvarian endometriosis is the most common type of endometriosis (EM), affecting more than 40% of women with EM. Currently, surgical intervention is still controversial in infertile patients with ovarian endometriosis, especially in those with stage  III–IV EM. Very few studies have been done to analyze long-term pregnancy results in patients with endometrioma more than 5 years after surgery. Therefore, the aim of this study was to explore the pregnancy outcomes and the related factors in patients with endometrioma and stage III–IV endom etriosis during a long-term follow-up pos...
Source: Advances in Therapy - Category: Drugs & Pharmacology Source Type: research
Conclusion: It is mandatory to point out that our conclusions are valid for patients with ovarian advanced endometriosis but normal ovarian functions. These results suggest three different progestins protocols are equivalent in terms of pregnancy outcomes for women with advanced endometriosis. PPOS protocol can be an alternative choice for women with severe endometriosis and normal ovarian reserve in IVF/ICSI treatment. These methods could be tested with other populations of women with endometriosis.Clinical Trial Registration:www.ClinicalTrials.gov, identifier:ChiCTR-OIN-16008529.Trial registration date: 2014-05-25.Date o...
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research
AbstractEndometriosis is a common entity causing chronic pain and infertility in women. The gold standard method for diagnosis is diagnostic laparoscopy, which is invasive and costly. MRI has shown promise in its ability to diagnose endometriosis and its efficacy for preoperative planning. The Society of Abdominal Radiology established a Disease-Focused Panel (DFP) to improve patient care for patients with endometriosis. In this article, the DFP performs a literature review and uses its own experience to provide technical recommendations on optimizing MRI Pelvis for the evaluation of endometriosis.
Source: Abdominal Imaging - Category: Radiology Source Type: research
Abstract Bisphenol-A (BPA) has been reported to be associated to female infertility. Indeed, BPA has been found to be more frequently detected in infertile women thus leading to hypothesize a possible effect of BPA on natural conception and spontaneous fecundity. In addition, in procedures of medically assisted reproduction BPA exposure has been found to be negatively associated with peak serum estradiol levels during gonadotropin stimulation, number of retrieved oocytes, number of normally fertilized oocytes and implantation. BPA deleterious effects are more critical during perinatal exposure, causing dysregulati...
Source: Reproductive Biology - Category: Reproduction Medicine Authors: Tags: Reprod Biol Endocrinol Source Type: research
ConclusionsThe prevalence of endometriosis in infertile women was higher than expected. The indication for operative infertility diagnostics by minimal invasive techniques should be made much more generous as well as the complete clarification of the causes of female infertility.
Source: Archives of Gynecology and Obstetrics - Category: OBGYN Source Type: research
reira Podgaec There is increasing interest in the potential of natural compounds to treat diseases, such as endometriosis, a gynecological disorder that affects 10%–15% of women of reproductive age, and it is related to severe pelvic pain and infertility. We have evaluated the in vitro effects of rutin and the aqueous bark, roots, and leaf extracts (ABE, ARE, and ALE, respectively) and isolated components of Uncaria guianensis on stromal cells from eutopic endometrium and lesions of patients with endometriosis. Two- and three-dimensional cultures were used to assess the cell death and production of reactiv...
Source: Molecules - Category: Chemistry Authors: Tags: Article Source Type: research
Study analysed data from more than 170,000 women born in Denmark between 1930 and 1996Girls who are tall and lean in childhood are more at risk of later developing endometriosis, research has found.Endometriosisis a painful, often debilitating, condition in which tissue similar to that found lining the womb is found elsewhere in the body, such as the bowel or ovaries. When it breaks down and bleeds, as it would in the womb, it can cause inflammation and pain. It is believed that up to 10% of women live with the condition, with some left infertile as a result.Continue reading...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Endometriosis Medical research Denmark Science World news Source Type: news
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