Knockout serum replacement is an efficient serum substitute for cryopreservation of human spermatozoa.

In conclusion, the addition of 10% KSR to the sucrose-based freezing solution improves the quality of post-thawed human spermatozoa and may have potential to develop chemically defined freezing medium.
PMID: 32004575 [PubMed - as supplied by publisher]

Source: Cryobiology - January 27, 2020 Category: Biology Authors: Taher-Mofrad SMJ, Topraggaleh TR, Ziarati N, Bucak MN, Nouri M, Seifi S, Esmaeili V, Rahimizadeh P, Shahverdi A Tags: Cryobiology Source Type: research