Pancreatic cancer symptoms: Five signs in your stools that may signal the deadly disease
PANCREATIC cancer is when uncontrollable cells multiply within the pancreas. The large gland is part of the digestive system, and so warning signs of the deadly condition could be flushed away in the toilet bowl.
British Journal of Cancer, Published online: 19 February 2020; doi:10.1038/s41416-020-0755-4HHLA2 is expressed in pancreatic and ampullary cancers and increased expression is associated with better post-surgical prognosis
len Bezak Pancreatic ductal adenocarcinoma (PDAC) has long been associated with lowαα survival rates. A lack of accurate diagnostic tests and limited treatment options contribute to the poor prognosis of PDAC. Radioimmunotherapy using α- or β-emitting radionuclides has been identified as a potential treatment for PDAC. By harnessing the cytotoxicity of α or β particles, radioimmunotherapy may overcome the anatomic and physiological factors which traditionally make PDAC resistant to most conventional treatments. Appropriate selection of target receptors and th...
Conditions: Microbial Colonization; Pancreas Cancer; Pancreas Infection; Pancreas; Fistula Intervention: Diagnostic Test: Microbiome evaluation Sponsor: Azienda Ospedaliera Universitaria Integrata Verona Recruiting
ConclusionPETCECT is a valuable tool to rule out metastatic disease in patients presenting with LAGBC.
The bromodomain and extra-terminal domain (BET) family of proteins, especially BRD4 play an important role in epigenetic regulation, and are essential for cell survival and also are promising anticancer target...
ConclusionFurther clinical trials are necessary to improve the identification of suitable patient cohorts and the extent of possible volume de-escalation that does not compromise tumor control.
ConclusionIn this paper, we present a robust approach for synthesizing a highly water-soluble fullerene nanoconjugate with gemcitabine. The performed biological assays on pancreatic cancer cell lines demonstrated cytotoxic effects of nanoC60GEM, which were enhanced by the generation of reactive oxygen species after blue LED irradiation of synthesized fullerene nanomaterial.