Diminishing returns from ultra-hypofractionated radiation therapy for prostate cancer

More than a decade of randomized controlled trials in prostate cancer have established a positive radiation dose response at moderate doses and a consistently low α/β ratio in the linear quadratic model for moderate hypofractionation. The recently published large randomized trial of ultra-hypofractionated prostate cancer radiotherapy adds substantially to our current knowledge of dose-response and fractionation sensitivity.
Source: International Journal of Radiation Oncology * Biology * Physics - Category: Radiology Authors: Source Type: research