Phase-separation in chromatin organization.

Phase-separation in chromatin organization.
J Biosci. 2020;45:
Authors: Narlikar GJ
Abstract
The organization of chromatin into different types of compact versus open states provides a means to fine tune gene regulation. Recent studies have suggested a role for phase-separation in chromatin compaction, raising new possibilities for regulating chromatin compartments. This perspective discusses some specific molecular mechanisms that could leverage such phase-separation processes to control the functions and organization of chromatin.
PMID: 31965983 [PubMed - in process]

Source: Journal of Biosciences - January 24, 2020 Category: Biomedical Science Authors: Narlikar GJ Tags: J Biosci Source Type: research