Pancreatoscopy-directed Electrohydraulic Lithotripsy in a Pediatric Patient With Pancreas Divisum and Cystic Fibrosis

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Source: Journal of Pediatric Gastroenterology and Nutrition - Category: Gastroenterology Tags: Video of the Month Source Type: research

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Authors: Fokkens WJ, Lund VJ, Hopkins C, Hellings PW, Kern R, Reitsma S, Toppila-Salmi S, Bernal-Sprekelsen M, Mullol J, Alobid I, Terezinha Anselmo-Lima W, Bachert C, Baroody F, von Buchwald C, Cervin A, Cohen N, Constantinidis J, De Gabory L, Desrosiers M, Diamant Z, Douglas RG, Gevaert PH, Hafner A, Harvey RJ, Joos GF, Kalogjera L, Knill A, Kocks JH, Landis BN, Limpens J, Lebeer S, Lourenco O, Matricardi PM, Meco C, O Mahony L, Philpott CM, Ryan D, Schlosser R, Senior B, Smith TL, Teeling T, Tomazic PV, Wang DY, Wang D, Zhang L, Agius AM, Ahlstrom-Emanuelsson C, Alabri R, Albu S, Alhabash S, Aleksic A, Aloulah M, Al-Qud...
Source: Rhinology - Category: ENT & OMF Tags: Rhinology Source Type: research
Authors: Annoni S, Bellofiore A, Repossini E, Lazzeri M, Nicolini A, Tarsia P Abstract Respiratory physiotherapy and rehabilitation are important therapeutic options in non-cystic fibrosis bronchiectasis (NCFB). The aims of this review of clinical trials were to evaluate the safety and the effects on physiologic and clinical outcomes of airway clearance techniques (ACTs) and rehabilitation in NCFB patients, in comparison to usual care. The search was performed on March 2018 by using PubMed and PeDro databases. 33 studies were selected. The use of ACTs for NCFB were effective in increasing sputum volume although no ...
Source: Monaldi Archives for Chest Disease - Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research
Condition:   Cystic Fibrosis Interventions:   Drug: CB-280;   Drug: Placebos Sponsor:   Calithera Biosciences, Inc Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
A heterogeneous liver pattern could indicate a higher risk for advanced cystic fibrosis liver disease
Source: Pulmonary Medicine News - Doctors Lounge - Category: Respiratory Medicine Tags: Family Medicine, Gastroenterology, Pathology, Pediatrics, Pulmonology, Radiology, Journal, Source Type: news
Pf bacteriophage are temperate phages that infect the bacterium Pseudomonas aeruginosa, a major cause of chronic lung infections in cystic fibrosis (CF) and other settings. Pf and other temperate phages have evolved complex, mutualistic relationships with their bacterial hosts that impact both bacterial phenotypes and chronic infection. We and others have reported that Pf phages are a virulence factor that promote the pathogenesis of P. aeruginosa infections in animal models and are associated with worse skin and lung infections in humans. Here we review the biology of Pf phage and what is known about its contributions to ...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
Leitão RNA-binding proteins (RBPs) are important regulators of cellular functions, playing critical roles on the survival of bacteria and in the case of pathogens, on their interaction with the host. RBPs are involved in transcriptional, post-transcriptional, and translational processes. However, except for model organisms like Escherichia coli, there is little information about the identification or characterization of RBPs in other bacteria, namely in members of the Burkholderia cepacia complex (Bcc). Bcc is a group of bacterial species associated with a poor clinical prognosis in cystic fibrosis patients. The...
Source: Genes - Category: Genetics & Stem Cells Authors: Tags: Article Source Type: research
We describe the variability of these infiltrates on CD3/CD20 duplex staining in renal biopsies of long-term functioning allografts, in breast cancer cases, and in lung tissue of cystic fibrosis patients. The assessment in cludes automated cell detection, identification of regions of interest, and classification of lymphocytic clusters according to their degree of organization. We propose a neighborhood feature which considers the occurrence of edges with a certain type in the graph to distinguish between phenotypical ly different immune infiltrates. Our work addresses a medical need and provides a scalable framework that c...
Source: PLoS Computational Biology - Category: Biology Authors: Source Type: research
Cystic fibrosis (CF) is a lethal inherited disease caused by mutations in the CF transmembrane conductance regulator (CFTR) gene, which result in impairment of CFTR mRNA and protein expression, function, stability or a combination of these. Although CF leads to multifaceted clinical manifestations, the respiratory disorder represents the major cause of morbidity and mortality of these patients. The life expectancy of CF patients has substantially lengthened due to early diagnosis and improvements in symptomatic therapeutic regimens. Quality of life remains nevertheless limited, as these individuals are subjected to conside...
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
THURSDAY, Feb. 20, 2020 -- A heterogeneous pattern on ultrasound examination of the liver may help identify children with cystic fibrosis (CF) at increased risk for developing advanced CF liver disease, according to a study published online Feb. 12...
Source: Drugs.com - Pharma News - Category: Pharmaceuticals Source Type: news
Condition:   Non-cystic Fibrosis Bronchiectasis Intervention:   Drug: Melphalan Sponsors:   Federal State Budgetary Institution, Pulmonology Scientific Research Institute;   Moscow State University of Medicine and Dentistry Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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