Strategic use of para-quinone methides to access synthetically challenging and chemoselective α,α′-diarylmethyl N-glycosides from unprotected carbohydrate amines

Org. Biomol. Chem., 2020, Accepted Manuscript DOI: 10.1039/D0OB00039F, CommunicationPintu Kumar Mandal, Rekha Sangwan, Atul Dubey, Ashwani Tiwari Reported herein is a practical route to access synthetically challenge and chemoselective α,α′-diarylmethyl N-glycosides via Sc(OTf)3-catalyzed 1,6-conjugate addition of amino sugars with para-quinone methides (p-QMs). The reactions proceed smoothly without... The content of this RSS Feed (c) The Royal Society of Chemistry

Source: RSC - Organic and Biomolecular Chemistry - January 23, 2020 Category: Molecular Biology Authors: Pintu Kumar Mandal Source Type: research