N-acetyl cysteine protects against chlorine-induced tissue damage in an ex vivo model.
In conclusion, Cl2 induced a concentration-dependent lung tissue damage that was effectively prevented with pre-treatment with NAC. There is a great need to improve the medical treatment of acute lung injury and this PCLS method offers a way to identify and to test new concepts of treatment of Cl2-induced lung injuries.
PMID: 31962155 [PubMed - as supplied by publisher]
Source: Toxicology Letters - Category: Toxicology Authors: Ågren L, Elfsmark L, Akfur C, Hägglund L, Ekstrand-Hammarström B, Jonasson S Tags: Toxicol Lett Source Type: research