Nonclinical safety assessment of repeated administration and biodistribution of ChAd3 ‐EBO‐Z Ebola candidate vaccine

In conclusion, the vaccine was locally and systemically well‐tolerated and the viral vector was partially or totally cleared from the organs where it disseminated, supporting the clinical development of the vaccine.

Source: Journal of Applied Toxicology - January 20, 2020 Category: Toxicology Authors: Camille Planty, Guillaume Chevalier, Marie ‐Ève Duclos, Clémentine Chalmey, Catherine Thirion‐Delalande, Cécile Sobry, Ann‐Muriel Steff, Eric Destexhe Tags: RESEARCH ARTICLE Source Type: research