Fluconazole Prophylaxis in Prevention of Symptomatic Candida Vaginitis

AbstractDue to broad spectrum susceptibility ofCandida species to fluconazole, its convenience as an oral agent, and predictable patient tolerance and safety, current practice guidelines recommend the use of long-term suppression regimens of fluconazole as prophylaxis for recurrent vulvovaginal candidiasis (RVVC), as well as in abbreviated doses when known trigger factors emerge and inevitable symptomatic episodes are predictable. However, recent concerns of fluconazole-resistantCandida albicans strains may impact fluconazole use, particularly, concerns of overuse. This literature review discusses current recommendations for prophylaxis of vulvovaginal candidiasis with fluconazole.
Source: Current Infectious Disease Reports - Category: Infectious Diseases Source Type: research