Experimental evidence for a role of dopamine on avian personality traits RESEARCH ARTICLE

Paulo A. Silva, Sandra Trigo, Cristiana I. Marques, Goncalo C. Cardoso, and Marta C. Soares There is increasing interest on the genetic and physiological bases of behavioural differences among individuals, namely animal personality. One particular dopamine (DA) receptor gene (the dopamine receptor D4 gene) has been used as candidate gene to explain personality differences, but with mixed results. Here we use an alternative approach, exogenously manipulating the dopaminergic system and testing for effects on personality assays in a social bird species, the common waxbill (Estrilda astrild). We treated birds with agonists and antagonists for DA receptors of both D1 and D2 pathways (the latter includes receptor D4) and found that short-term manipulation of DA signalling had an immediate effect on personality-related behaviours. In an assay of social responses (mirror test), manipulation of D2 receptor pathways reduced time spent looking at the social stimulus (mirror image). Blocking D2 receptors reduced motor activity in this social assay, while treatment with D2 agonist augmented activity in this social assay but reduced activity in a non-social behavioural assay. Also, in the non-social assay, treatment with the D1 antagonist markedly increased time spent at the feeder. These results show distinct and context-specific effects of the dopaminergic pathways on waxbill personality traits. Our results also suggest that experimental manipulation of DA signalling can disrupt a behav...
Source: Journal of Experimental Biology - Category: Biology Authors: Tags: RESEARCH ARTICLE Source Type: research

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In this study, we collected 693 nasal swab samples and 800 blood samples from stray dogs in animal shelters to survey canine influenza epidemiology and characterize the evolution of CIV H3N2 in Shanghai. We tested samples for canine influenza antibodies and canine influenza RNA in January –May, 2019, and the results showed that the positive rate was 17.62% by ELISA, 15.75% by microneutralization (MN) assay, and 18.51% by real time RT-PCR, respectively. We also performed phylogenetic and genomic analysis on six H3N2 CIV isolates. The H3N2 viruses which prevailed in Shanghai originat ed from Beijing and Jiangsu isolate...
Source: Virus Genes - Category: Genetics & Stem Cells Source Type: research
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Source: EurekAlert! - Infectious and Emerging Diseases - Category: Infectious Diseases Source Type: news
Contributors : Qingtao Liu ; Yin Li ; Jing YangSeries Type : Expression profiling by high throughput sequencingOrganism : Gallus gallusWe analyze the differentially expressed genes (DEGs) at the transcriptome level in chicken DCs infected with H9N2 influenza virus compared to mock infection by high-throughput RNA-sequencing technology, and found that H9N2 influenza virus infection induced a strong innate immune response in chicken DCs, but impaired the antigen-processing and –presenting capacity of this cell,
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Gallus gallus Source Type: research
Research in chickens has been fundamental for the discovery of basic aspects of the immune system and has led to an interest in the in-depth characterization of avian immune cell types including dendritic cells (DCs). The in vitro generation and expansion of chicken bone marrow-derived DCs (chBMDCs) in the presence of granulocyte-macrophage colony-stimulating factor (GM-CSF) has provided a way to study chicken DCs, which are only present at limited cell numbers in vivo. This method has been employed to study the interactions between chicken DCs and pathogens or vaccines. However, a detailed characterization of the chBMDC c...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
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Source: Pharmacology and Therapeutics - Category: Drugs & Pharmacology Source Type: research
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Source: PLoS Neglected Tropical Diseases - Category: Tropical Medicine Authors: Source Type: research
Publication date: Available online 22 February 2020Source: Progress in NeurobiologyAuthor(s): William James Clark, Michael ColomboAbstractWe provide an extensive review of the pigeon visual system, focussing on the known cell types, receptive field characteristics, mechanisms of perception/visual attention, and projection profiles of neurons in the thalamofugal and tectofugal pathways. The similarities and differences with the primate visual system at each stage of the visual hierarchy are highlighted. We conclude with a discussion of object and face processing in birds, as well as the current state of knowledge in the sea...
Source: Progress in Neurobiology - Category: Neuroscience Source Type: research
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Source: Military Medicine - Category: International Medicine & Public Health Tags: Mil Med Source Type: research
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Source: Frontiers in Physiology - Category: Physiology Source Type: research
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Source: Polish Journal of Microbiology - Category: Microbiology Tags: Pol J Microbiol Source Type: research
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