To start or to complete? - Challenges in implementing tuberculosis preventive therapy among people living with HIV: a mixed-methods study from Karnataka, India.

Conclusion: The combined picture of 'low IPT initiation and high completion' seen in our study mirrors findings from other countries. Drug stock-out was the key challenge, which obliged health-care providers to prioritize 'IPT completion' over 'IPT initiation'. There is an urgent need to improve the procurement and supply chain management of isoniazid. PMID: 31937200 [PubMed - in process]
Source: Global Health Action - Category: International Medicine & Public Health Tags: Glob Health Action Source Type: research

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Authors: Rahim MA, Zaman S, Amin MR, Uddin KN, Ma JC Abstract Histoplasmosis is uncommon in many parts of the world, including Bangladesh, where, in recent years, cases are increasingly reported. We sought to describe the sociodemographic characteristics, clinical presentation, investigations, treatment, and outcome of histoplasmosis in Bangladesh. We conducted a retrospective data review of published literature from 1962 to 2017, containing information on histoplasmosis in and/or from Bangladesh. Unpublished, well-documented histoplasmosis cases were also included. A total of 26 male patients aged 8-75 years, with...
Source: Oman Medical Journal - Category: Middle East Health Tags: Oman Med J Source Type: research
Conclusion: The presence of 2 or more independent PoCUS predictors (intra-abdominal lymphadenopathy, ascites, and pericardial effusion) had moderate discrimination for HIV-associated tuberculosis in patients presenting to the emergency center.
Source: JAIDS Journal of Acquired Immune Deficiency Syndromes - Category: Infectious Diseases Tags: Clinical Science Source Type: research
CONCLUSIONS: Tuberculous pericarditis with pericardial effusion without constrictive physiology is unlikely to develop into constrictive pericarditis in immunocompetent hosts, if treated with optimal anti-tuberculous medication and steroid therapy. Even though there were hemodynamic feature of constrictive pericarditis, more than 80% of the patients were improved from constrictive pericarditis. PMID: 32096358 [PubMed - as supplied by publisher]
Source: Korean Circulation Journal - Category: Cardiology Tags: Korean Circ J Source Type: research
[Vanguard] Abuja -No fewer than 581,000 Nigerians have received treatment for Tuberculosis between 2015 and 2020 in 12 states of the country, the United States Agency for International Development (USAID) has said.
Source: AllAfrica News: Tuberculosis - Category: Infectious Diseases Source Type: news
[Vanguard] President of the Senate, Ahmad Lawan, has appealed to the United Nations (UN) and the World Health Organisation (WHO) to lend their support to the Nigerian Government towards ensuring the eradication of tuberculosis in the country.
Source: AllAfrica News: Tuberculosis - Category: Infectious Diseases Source Type: news
Authors: Miller A, Cairns A, Richardson A, Lawrence J Abstract CONTEXT: Tuberculosis (TB) is a serious infectious disease with high rates of morbidity and mortality if left untreated. In Australia, TB has been virtually eradicated in non-Indigenous Australian-born populations but in remote Aboriginal and/or Torres Strait Islander communities TB presents a rare but significant public health issue. Remote health services are most likely to encounter patients with suspected and confirmed TB diagnosis but may be unprepared for supporting someone with this disease and the complexities of balancing public health risk wit...
Source: Rural and Remote Health - Category: Rural Health Tags: Rural Remote Health Source Type: research
Tuberculosis (TB) remains a major health threat. Although a vaccine has been available for almost 100 years termed Bacille Calmette-Guérin (BCG), it is insufficient and better vaccines are urgently needed. This treatise describes first the basic immunology and pathology of TB with an emphasis on the role of T lymphocytes. Better understanding of the immune response to Mycobacterium tuberculosis (Mtb) serves as blueprint for rational design of TB vaccines. Then, disease epidemiology and the benefits and failures of BCG vaccination will be presented. Next, types of novel vaccine candidates are being discussed. These i...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
Background A large proportion of the huge global burden of extrapulmonary tuberculosis (EPTB) cases are treated empirically without accurate definition of disease sites and extent of multi-organ disease involvement. Positron emission tomography (PET) imaging using 2-deoxy-2-(fluorine-18) fluoro-d-glucose (18F-FDG) in tuberculosis could be a useful imaging technique for localising disease sites and extent of disease. Methods We conducted a study of HIV-negative adult patients with a new clinical diagnosis of EPTB across eight centres located in six countries: India, Pakistan, Thailand, South Africa, Serbia and Bangladesh, ...
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Lung imaging, Respiratory infections and tuberculosis Original Articles: Tuberculosis and imaging Source Type: research
Conclusions: Bronchoscopic device closure can be a successful strategy to manage postoperative BPF with minimal complications.
Source: Lung India - Category: Respiratory Medicine Authors: Source Type: research
Conclusions: The examination of serum ADA levels can be used to evaluate the PTB treatment response.
Source: Lung India - Category: Respiratory Medicine Authors: Source Type: research
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