Frequency and expression of st313-td gene and virulence of Salmonella Dublin strains isolated from humans and animals in Brazil.

In conclusion, the presence of st313-td in all the S. Dublin strains studied besides its expression among strains from invasive cases suggest that this gene might be related to the invasive characteristic of this serovar. The low expression of sopE2 in strains from human invasive cases suggests that the expression of this gene may not be a limiting factor to the invasion of S. Dublin strains. Moreover, the absence fliC expression and the low motility rates observed suggest that the flagella absence may favor the host immune system evasion by S. Dublin and the establishment of invasive infection. The high invasion to human epithelial cells and survival within human macrophages, besides the high mortality rates observed in vivo, reinforce the invasive potential of S. Dublin strains.
PMID: 31931258 [PubMed - as supplied by publisher]

Source: Infection, Genetics and Evolution - January 9, 2020 Category: Genetics & Stem Cells Authors: Vilela FP, Gomes CN, Paziani MH, Braz VS, Dos Prazeres Rodrigues D, Costa RG, Casas MRT, von Zeska Kress MR, Falcão JP, Campioni F Tags: Infect Genet Evol Source Type: research