Response to letter by Messeri et al

We thank Dr Messeri and colleagues for their interest in our network meta-analysis on the risk of stroke in patients treated with on-pump coronary artery bypass graft (CABG), off-pump CABG, and percutaneous coronary intervention (PCI), which builds upon a prior comprehensive pairwise analysis on the same topic. The crude event rates by simple pooling of data are 148/10,957 (1.4%) for 79 studies of on-pump CABG, 72/7,119 (1.0%) for 70 studies of off-pump CABG, and 15/4,653 (0.3%) for 17 studies of PCI. From a Bayesian binomial random-effect model, the absolute risk estimate for stroke was 1.4% in patients treated with on-pump CABG, 0.9% in patients treated with off-pump CABG, and 0.4% in patients treated with PCI.
Source: American Heart Journal - Category: Cardiology Authors: Tags: Letters to the Editor Source Type: research