Bone union formation in the rat mandibular symphysis using hydroxyapatite with or without simvastatin: effects on healthy, diabetic, and osteoporotic rats

ConclusionsCombined application of HA and SV improves bone regeneration in mandibular critical bone defects compared with application of HA alone in healthy, diabetic, and osteoporotic rats.Clinical relevanceThis study might help to patients with osteoporosis or uncontrolled diabetes type 1, but future studies should be done.

http://link.springer.com/10.1007/s00784-019-03180-9

Source: Clinical Oral Investigations - January 10, 2020 Category: Dentistry Source Type: research