Systemic activation of NLRP3 inflammasome and plasma α-synuclein levels are correlated with motor severity and progression in Parkinson’s disease

Emerging evidence indicates that inflammasome-induced inflammation plays a crucial role in the pathogenesis of Parkinson ’s disease (PD). Several proteins including α-synuclein trigger the activation of NLRP3 i...

Source: Journal of Neuroinflammation - January 8, 2020 Category: Neurology Authors: Zheng Fan, Yu-Ting Pan, Zhi-Yuan Zhang, Hui Yang, Shu-Yue Yu, Yan Zheng, Jing-Hong Ma and Xiao-Min Wang Tags: Research Source Type: research