Fibroblast-derived non-canonical WNT ligands contribute to attenuated alveolar epithelial repair in COPD
Conclusion: In COPD, attenuated canonical WNT signaling and disturbed alveolar epithelial cell repair may be a consequence of a shift in conditions that triggers WNT-5A secretion by fibroblasts.
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Baarsma, H. A., Boczkowski, J., Yildirim, A. O., Konigshoff, M. Tags: 3.3 Mechanisms of Lung Injury and Repair Source Type: research
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