Two MRI indicators predict Fabry disease adverse events

How can clinicians best use cardiac MRI to identify which patients with Fabry...Read more on AuntMinnie.comRelated Reading: Imaging criteria for congenital heart disease released 3D printing helps unravel rare cardiac anomalies 3D MRI enables contrast-free evaluation of cardiac strain Cardiac MRI plan hikes myocarditis detection rate MRI aids in assessing cocaine-related heart damage
Source: Headlines - Category: Radiology Source Type: news

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Shenmai injection suppresses multidrug resistance in MCF-7/ADR cells through the MAPK/NF-κB signalling pathway. Pharm Biol. 2020 Dec;58(1):276-285 Authors: Yang L, Zhang C, Chen J, Zhang S, Pan G, Xin Y, Lin L, You Z Abstract Context: Shenmai Injection (SMI) is usually used to treat atherosclerotic coronary heart disease and viral myocarditis in China. However, the effect of SMI on multidrug resistance has not been reported.Objective: To investigate the reversal effect of SMI in adriamycin (ADR) resistant breast cancer cell line (MCF-7/ADR) and explore the related molecular mechanisms.Materials a...
Source: Pharmaceutical Biology - Category: Drugs & Pharmacology Tags: Pharm Biol Source Type: research
Universal approaches to the prevention and treatment of human diseases fail to take into account profound immune diversity resulting from genetic variations across populations. Personalized or precision medicine takes into account individual lifestyle, environment, and biology (genetics and immune status) and is being adopted in several disease intervention strategies such as cancer and heart disease. However, its application in infectious diseases, particularly global diseases such as tuberculosis (TB), is far more complex and in a state of infancy. Here, we discuss the impact of human genetic variations on immune respons...
Source: Frontiers in cellular and infection microbiology - Category: Microbiology Source Type: research
Purpose of review Orthotopic heart transplantation (OHT) significantly improves morbidity and mortality in patients with end-stage heart disease. Despite advances in surgical technique, immunosuppressive therapies, and patient monitoring, long-term risk of arrhythmias and sudden cardiac death (SCD) in the denervated heart remains unchanged. Recent findings SCD is responsible for approximately 10% of all posttransplant deaths with a pooled incidence rate of 1.30 per 100 person years and is strongly associated with cardiac allograft vasculopathy (CAV). Risk factors for SCD and CAV include higher donor age, younger recip...
Source: Current Opinion in Cardiology - Category: Cardiology Tags: CARDIAC FAILURE: Edited by Rebecca Cogswell and Gene Kim Source Type: research
As the COVID-19 pandemic plagues the world, the head of the UN peacekeeping mission in Mali told the Security Council on Tuesday that the mission continues to fulfill its mandate while doing whatever it can to prevent the coronavirus outbreak from overrunning the country.
Source: UN News Centre - Health, Poverty, Food Security - Category: International Medicine & Public Health Source Type: news
Does a cell surface protein explain why the coronavirus is more likely to kill people with diabetes or heart disease? Researchers are trying to find out
Source: New Scientist - Health - Category: Consumer Health News Source Type: research
TUESDAY, April 7, 2020 -- Long-term heavy drinking may lead to significant weight gain and an increased risk of heart disease and stroke in older adults, British researchers warn. They analyzed data from more than 4,800 U.K. civil servants who were...
Source: - Daily MedNews - Category: General Medicine Source Type: news
TUESDAY, April 7, 2020 -- Genetic testing is not better at predicting coronary heart disease risk compared with conventional risk factors, according to a study published in a recent issue of the Journal of the American Medical Association. Jonathan...
Source: - Pharma News - Category: Pharmaceuticals Source Type: news
Conditions:   Congenital Heart Disease;   Covid-19 Intervention:   Sponsors:   University Hospital, Montpellier;   Pr. Jean-Benoît THAMBO, Bordeaux (président);   Dr. Céline GRUNENWALD GRONIER, Strasbourg;   Dr. Sébastien HASCOET, Le Plessis-Robinson;   Dr. Adeline BASQUIN, Rennes;   Dr. Nicolas COMBES, Toulouse;   Dr. Xavier IRIART, Bordea ux;   Dr. Daniela LAUX, Paris;   Dr. Magalie LADOU...
Source: - Category: Research Source Type: clinical trials
Conclusion Patients’ responses highlighted the need to increase individuals’ awareness on the first signs and symptoms of the disease. The survey also showed that chronic stable angina patients need constant emotional support to overcome stress, anxiety, and depression. Finally, this study suggests the need to offer greater space for dialogue with healthcare professionals to get more comprehensive and ‘patient-friendly’ information.
Source: Journal of Cardiovascular Medicine - Category: Cardiology Tags: Research articles: Coronary artery disease Source Type: research
Swiss and German researchers have devised an effective diagnostic cardiac MRI...Read more on AuntMinnie.comRelated Reading: Is perfusion MRI best to rule on revascularization? MRI aids in assessing cocaine-related heart damage AI model could enable gadolinium-free cardiac MRI Cardiac MRI flags signs of early heart disease in women Underutilized cardiac MRI stress test predicts mortality
Source: Headlines - Category: Radiology Source Type: news
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