Antioxidant effects of dexmedetomidine against hydrogen peroxide-induced DNA damage in-vitro by alkaline comet assay.

CONCLUSION: There is limited data on protective effects of DEX against oxidative DNA damage. The primary effect might be cytoprotection. Our results showed that dexmedetomidine is protective against H2O2 induced in vitro oxidative DNA damage in lymphocyte cell cultures in a dose-dependent manner. DEX might have a potential therapeutic value in the prevention of oxidative DNA damage in patients. PMID: 31905495 [PubMed - as supplied by publisher]
Source: Turkish Journal of Medical Sciences - Category: General Medicine Tags: Turk J Med Sci Source Type: research