Nuclear IL-33 arguments ST2 receptor expression in pulmonary arterial endothelial cells: Implication in the pathogenesis and progression of pulmonary arterial hypertension

Conclusion: IL-33 regulates the expression of IL-6 and sST2, an endogenous IL-33 inhibitor, and may play an important role in the pathogenesis of PAH.Funded by:The Doverdale Trust, Royal Brompton Hospital, London, UK.

Source: European Respiratory Journal - December 23, 2014 Category: Respiratory Medicine Authors: Shao, D., Perros, F., Meng, C., Caramori, G., Humbert, M., Chou, P.-C., Adcock, I., Wort, S. Tags: 4.3 Pulmonary Circulation and Pulmonary Vascular Disease Source Type: research