COPD and lung cancer incidence in the Women ’s Health Initiative Observational Study: A brief report

Lung cancer is the leading cause of cancer mortality in both men and women in the United States, with an estimated 154,050 deaths expected to occur in 2018 [1]. Cigarette smoking has been linked to the development of lung cancer and chronic obstructive pulmonary disease (COPD) [2] and COPD has been found to be independently associated with an increased risk of developing lung cancer. A pooled analysis of 17 epidemiologic studies reported a 2.4-fold increase in risk of lung cancer associated with emphysema (ORmeta  = 2.44, 95% CI: 1.64, 3.62), and a 1.5-fold association with chronic bronchitis (ORmeta = 1.47, 95% CI: 1.29-1.68) after adjusting for smoking history; however, estimates were not provided separately for men and women [3].

Source: Lung Cancer - January 6, 2020 Category: Cancer & Oncology Authors: Misako Nagasaka, Amy Lehman, Rowan Chlebowski, Brittany M. Haynes, Gloria Ho, Manali Patel, Lori C. Sakoda, Ann G. Schwartz, Michael S. Simon, Michele L. Cote Source Type: research