Thyroid hormones T3 and T4 regulate human luteinized granulosa cells, counteracting apoptosis and promoting cell survival

ConclusionFrom the present study, THs emerge as potent anti-apoptotic agents in hGL cells. This effect is achieved by inhibiting the apoptosis signalling pathway of BAX and caspase-3, while maintaining active the PI3K/AKT pathway.

http://link.springer.com/10.1007/s40618-019-01169-5

Source: Journal of Endocrinological Investigation - December 31, 2019 Category: Endocrinology Source Type: research