372: Intrauterine fluid management during in-utero spina bifida repair and its effect on preterm delivery

Effects of continuous infusion (CI) of Lactated Ringers solution (LR) and replacement of the lost amniotic fluid (AF) with the LR during in-utero spina bifida (SB)repair surgery on the preterm birth remains unknown. AF nourishes the avascular amniotic membranes, replacing it with LR may cause preterm birth. We evaluated the effects of CI and volume replacement with LR or AF at the end of the surgery on the gestational age (GA) at delivery. Additionally, in-vitro studies were conducted to test the effects of dilution of AF with LR on human amniotic epithelial cells (HAEpiC).
Source: American Journal of Obstetrics and Gynecology - Category: OBGYN Authors: Tags: Poster Session II Source Type: research