Oral manifestations of the cowden syndrome: case report

Cowden syndrome (CS) is an autosomal dominant disease with increased risk of breast, thyroid, and endometrial malignant neoplasms as well as mucocutaneous lesions. A 63-year-old woman with previous diagnosis of CS was referred to our oral diagnostic clinic complaining of a painless nodule on the left buccal mucosa with history of trauma. The patient also had a history of multiple facial trichilemmomas, palmoplantar keratosis, gastrointestinal polyps, hemangioma on the left upper limb, liposarcoma in the inframammary region, abdominal dermatofibrosarcoma protuberans, and follicular adenoma in the thyroid.
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - Category: ENT & OMF Authors: Source Type: research