Structure‐guided design affirms inhibitors of hepatitis C virus p7 as a viable class of antivirals targeting virion release

Conclusions: This proof‐of‐principle that structure‐guided design can lead to drug‐like molecules affirms p7 as a much needed new target in the burgeoning era of HCV DAA. (Hepatology 2013;)

Source: Hepatology - August 12, 2013 Category: Internal Medicine Authors: Toshana L. Foster, Gary S. Thompson, Arnout P. Kalverda, Jayakanth Kankanala, Matthew Bentham, Laura F. Wetherill, Joseph Thompson, Amy M. Barker, Dean Clarke, Marko Noerenberg, Arwen R. Pearson, David J. Rowlands, Steven W. Homans, Mark Harris, Richard F Tags: Viral Hepatitis Source Type: research