Botulinum toxin type a for first bite syndrome - a case report

Introduction: First bite syndrome (FBS) – a condition first described in 1986 by Haubrich, is a condition typified as intense, often neuralgic pain in the parotid gland on the first bite of food, that decreases in severity with each further bite1-4. The condition most commonly occurs following surgery to the parotid gland, within the pa rapharyngeal or infratemporal space. Adenervation injury can result in hypersensitivity of the sympathetic fibres that supply the myoepithelial cells of the parotid4.
Source: The British Journal of Oral and Maxillofacial Surgery - Category: ENT & OMF Authors: Tags: P194 Source Type: research

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This article studied their effect in pediatrics:https://www.ahajournals.org/doi/full/10.1161/CIRCEP.109.901629===================================MY Comment by KEN GRAUER, MD (5/30/2020):===================================Fascinating case presented by Dr. Smith (!) — about this young woman who presented with palpitations and sequential reentry SVT rhythms — initially at a ventricular rate of ~160/minute — and then following administration of 6mg IV adenosine, another reentry SVT at a much faster rate of ~240/minute. HOW could this happen?For ...
Source: Dr. Smith's ECG Blog - Category: Cardiology Authors: Source Type: blogs
AbstractObjectivesTo explore the effects and mechanisms of transcutaneous electrical acustimulation (TEA) on postoperative recovery after cesarean section (CS).Materials and MethodsA total of 108 women who underwent CS were randomized to receive TEA or sham ‐TEA. Four hours after CS, electrogastrogram (EGG) and electrocardiogram (ECG) were recorded for 30 min to assess gastric slow waves and autonomic functions, respectively. TEA at ST36 or sham‐TEA at non‐acupoints was performed for one hour right after recording ECG and EGG and then twice d aily from postoperative days (POD) 1 to 3. In the morning of ...
Source: Neuromodulation: Technology at the Neural Interface - Category: Biotechnology Authors: Tags: Clinical Research Source Type: research
If you struggle with suicide, depression or anxiety, the types of people you have in your support network can make the difference between them being a lifeline or a weight.It ’s been over two years since I was last suicidal. I wasn’t making dark and deadly plans at the time. I simply thought I would be better off dead. It was the matter-of-factness of the “epiphany” that startled me the most. It seemed perfectly logical. Fortunately, I’ve heard thislogic before and immediately engaged my coping strategies. I let family members know, I prayed deeply, and since I didn ’t have a current cou...
Source: The Splintered Mind by Douglas Cootey - Category: Psychiatry Tags: Depression Goodreads Suicide Source Type: blogs
In conclusion, our results suggest a previously unknown mechanism whereby the canonical NF-κB cascade and a mitochondrial fission pathway interdependently regulate endothelial inflammation. Lin28 as a Target for Nerve Regeneration https://www.fightaging.org/archives/2020/05/lin28-as-a-target-for-nerve-regeneration/ Researchers here show that the gene Lin28 regulates axon regrowth. In mice, raised levels of Lin28 produce greater regeneration of nerve injuries. Past research has investigated Lin28 from the standpoint of producing a more general improvement in regenerative capacity. It improves mitoch...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Diabetes is a worldwide public health concern as it is associated with various complications. One of the major complications of diabetes is diabetic foot syndrome that results in catastrophic events such as ulceration and amputation. Therefore, the main four strategies of diabetic foot care involve risk prediction, prevention, and early diagnosis and prompt intervention. The drivers of ulceration are multifactorial, and importantly, include microcirculatory changes in the diabetic skin. Cutaneous microcirculation on the foot is greatly influenced by the small fibers which mediate thermal sensation and pain perception in ad...
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research
CONCLUSION: EA activates the sympathetic nervous system and induces the release of epinephrine, which could ameliorate inflammation and protect muscular tissue in addition to relieving pain. PMID: 32429680 [PubMed - as supplied by publisher]
Source: Acupuncture in Medicine : journal of the British Medical Acupuncture Society - Category: Complementary Medicine Authors: Tags: Acupunct Med Source Type: research
Follistatin is an inhibitor of myostatin. Blocking myostatin activity enhances muscle growth, with accompanying beneficial side-effects such as a loss of excess fat tissue. This is well proven. There are a good number of animal lineages (mice, dogs, cows, and so forth) resulting from natural or engineered myostatin loss of function mutations, and even a few well-muscled human individuals with similar mutations. A number of groups are at various stages in the development of therapies to either upregulate follistatin or inhibit myostatin. The latter is further along in the formal regulatory process: human trials have been co...
Source: Fight Aging! - Category: Research Authors: Tags: Medicine, Biotech, Research Source Type: blogs
Conclusions Local sympathetic nerves control the progression of immune responses in dorsal root ganglia and pain-like behaviors in mice after paclitaxel, raising the possibility that clinical strategies already in use for local sympathetic blockade may also offer an effective treatment for patients experiencing chemotherapy-induced neuropathic pain.Editor ’s PerspectiveWhat We Already Know about This TopicChemotherapy-induced neuropathic pain is a common and difficult-to-treat problemInflammation may support chemotherapy-induced pain by interacting with sensory neuronsWhat This Article Tells Us That Is NewLocal surgi...
Source: Anesthesiology - Category: Anesthesiology Source Type: research
A 60-something man presented by EMS with 5 hours of fairly typical sounding substernal chest pain. Here is the EMS ECG:Obviously massive diffuse subendocardial ischemia, with profound STD and STE in aVROf course this pattern is most often seen from etoliogies other than ACS.  The ECG only tells you there is ischemia, not the etiology of it.Nevertheless, the clinical situation made other etiologies unlikely.EMS gave 324 mg aspirin and 3 sublingual NTG, which the patient stated reduced the substernal chest pain from an 8/10 to 4/10.Here is the ED ECG on arrival:Less STE/STDProvider's Clinical Impression: ...
Source: Dr. Smith's ECG Blog - Category: Cardiology Authors: Source Type: blogs
ke MA Abstract Chronic cancer-related symptoms (stress, fatigue, pain, depression, insomnia) may be linked with sympathetic nervous system over-activation and autonomic imbalance. Decreased heart rate variability (HRV) is an indicator of autonomic dysregulation that is commonly observed among cancer survivors. HRV biofeedback (HRVB) training induces HRV coherence, which maximizes HRV and facilitates autonomic and cardiorespiratory homeostasis. This randomized, wait-list-controlled, pilot intervention trial tested the hypothesis that HRVB can improve HRV coherence and alleviate cancer-related symptoms. The interven...
Source: Applied Psychophysiology and Biofeedback - Category: Psychiatry & Psychology Authors: Tags: Appl Psychophysiol Biofeedback Source Type: research
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