Allergic skin diseases beyond TH2

Recent studies have highlighted the multidimensional effect of atopic dermatitis (AD) and urticaria. Patient burden for these conditions is largely driven by the intense itching, sleep disturbance, comorbidities, and mental health illness associated with these diseases.1-3 Immunologic, microbial, and epithelial interactions have been reported to play an important role in AD.4,5 Novel therapies and management approaches are targeting the mechanisms underlying AD and urticaria.6,7 The current issue of the Annals contains 3 outstanding reviews that update readers on the pathophysiology and evolving treatments for AD and chronic urticaria.
Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Tags: Editorial Source Type: research

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Although sleep is ubiquitous, its evolutionary purpose remains elusive. Though every species of animal, as well as many plants sleep, theories of its origin are purely physiological, e.g. to conserve energy, make repairs or to consolidate learning. An evolutionary reason for sleep would answer one of biology ’s fundamental unanswered questions. When environmental conditions change on a periodic basis (winter/summer, day/night) organisms must somehow confront the change or else be less able to compete in either niche. Seasonal adaptation includes the migration of birds, changes in honeybee physiology a nd winter absci...
Source: Journal of Circadian Rhythms - Category: Biology Source Type: research
ConclusionsThe findings suggest children with 22q11DS may have a higher risk of experiencing clinical sleep problems, compared to typically developing children. Consideration of additional screening and treatment of sleep disorders in children with 22q11DS is warranted.
Source: Molecular Genetics & Genomic Medicine - Category: Genetics & Stem Cells Authors: Tags: ORIGINAL ARTICLE Source Type: research
CONCLUSION Infrastructural adequacy of PHCC was associated with less PCSC hospitalizations, while availability medical professional and medications were associated with higher PCSC hospitalizations.
Source: Revista de Saude Publica - Category: International Medicine & Public Health Source Type: research
STUDY OBJECTIVES: To compare rail workers' actual sleep-wake behaviors in normal operations to those predicted by a biomathematical model of fatigue (BMMF). To determine whether there are group-level residual sources of error in sleep predictions that coul...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Distraction, Fatigue, Chronobiology, Vigilance, Workload Source Type: news
Abstract Good sleep is considered to be the cornerstone for maintaining both physical and mental health. However, nearly one billion people worldwide suffer from various sleep disorders. To date, polysomnography (PSG) is the most commonly used sleep-monitoring technology,however, it is complex, intrusive, expensive and uncomfortable. Unfortunately, present noninvasive monitoring technologies cannot simultaneously achieve high sensitivity, multi-parameter monitoring and comfort. Here, we present a single-layered, ultra-soft, smart textile for all-around physiological parameters monitoring and healthcare during slee...
Source: Biosensors and Bioelectronics - Category: Biotechnology Authors: Tags: Biosens Bioelectron Source Type: research
Anyone have any insight on Allergy&Immunology job market, lifestyle, and salary? Have heard that field is struggling in PP due to primary care docs taking over procedures but I wonder how true this is especially in urban centers like SF/LA/NYC/Chicago/Miami?
Source: Student Doctor Network - Category: Universities & Medical Training Authors: Tags: Other Subspecialties Source Type: forums
Publication date: March–April 2020Source: Heart &Lung, Volume 49, Issue 2Author(s): William Abraham, Ralph Augostini, Ayesha Hasan, Seamus Jackson, Rami Kahwash, Julie Mease, Emani Sitaramesh
Source: Heart and Lung: The Journal of Acute and Critical Care - Category: Respiratory Medicine Source Type: research
Publication date: March–April 2020Source: Heart &Lung, Volume 49, Issue 2Author(s): Martha Abshire, Juliet Duran, Nisha Gilotra, Hannah Jacob, Mei Ching Lee, Kayla O'Neil, Mirlene Perry, Regina Porter, Tania Randell, Stuart Russell, Rachel Sanford
Source: Heart and Lung: The Journal of Acute and Critical Care - Category: Respiratory Medicine Source Type: research
Discussion Atopic dermatitis (AD) has a prevalence of 3-5% in the overall U.S. population but is increasing with an estimated 10-15% lifetime risk in childhood. It is even more common in children of color with a prevalence in African-American/black children of 17% and Hispanic children of 14%. Health care utilization data also appears to support more severe disease in children of color also. Atopic dermatitis or eczema is a common dermatological skin problem which characteristically is a pruritic, papular eruption with erythema. Like most papulosquamous eruptions it often occurs in intertrigenous areas in people with alle...
Source: PediatricEducation.org - Category: Pediatrics Authors: Tags: Uncategorized Source Type: news
DISCUSSION SESSION 1: Food allergy (PD01 –PD05)PD01 Allergen-specific humoral and cellular responses in children who fail egg oral immunotherapy due to allergic reactionsMarta Vazquez-Ortiz, Mariona Pascal, Ana Maria Plaza, Manel JuanPD02 FoxP3 epigenetic features in children with cow milk allergyLorella Paparo, Rita Nocerino, Rosita Aitoro, Ilaria Langella, Antonio Amoroso, Alessia Amoroso, Carmen Di Scala, Roberto Berni CananiPD04 Combined milk and egg allergy in early childhood: let them eat cake?Santanu Maity, Giuseppina Rotiroti, Minal GandhiPD05 Introduction of complementary foods in relation to allergy and gut...
Source: Clinical and Translational Allergy - Category: Allergy & Immunology Source Type: research
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