HRG-beta1-driven ErbB3 signaling induces epithelial--mesenchymal transition in breast cancer cells

Conclusions: Our data suggest that HRG-beta1 and ErbB3 induce EMT, cancer cell migration and invasion through the PI3k/Akt-phospho-Smad2-Snail signaling pathway in SK-BR-3 and MCF7 breast cancer cells.
Source: BMC Cancer - Category: Cancer & Oncology Authors: Source Type: research