Application of a New Multiplexed Array for Rapid, Sensitive, Simultaneous and Quantitative Assessment of Spliced and Unspliced XBP1.

Conclusions: The XBP1 biochip enables isoform specific quantification of protein level changes upon activation and inhibition of IRE1α RNase activity, using a routine clinical methodology. As such it provides a research tool and potential clinical tool with a quantified, simultaneous, rapid output that is not available from any other published method.
PMID: 31807121 [PubMed]

Source: Biological Procedures Online - December 7, 2019 Category: Molecular Biology Authors: Creedican S, Talty A, Fitzgerald SP, Samali A, Richardson C, Gorman AM, Martin K Tags: Biol Proced Online Source Type: research