Diagnostic Errors in Clinical Microbiology and Antimicrobial Resistance
Publication date: Available online 4 December 2019Source: Current Medicine Research and PracticeAuthor(s): Tulsi ChughAbstractAntimicrobial resistance (AMR) is a serious public health threat worldwide, and is leading to resurgence of untreatable infectious diseases. However, AMR surveillance in low and middle-income countries (LMICs) may not be of appropriate level. Optimum utilisation of clinical microbiology services requires an integrated effort of several hospital services including supportive management and dedicated nursing staff. It requires regular and persistent motivation at all levels of the healthcare.
ConclusionThis is the first report showing the high prevalence of carbapenemases in ESBL-positive isolates in this area. Regular surveillance for such resistance mechanisms will be useful for health personnel to treat infections by these multidrug-resistant pathogens.
[Ghanaian Times] There is concern about the effects of irrational use of antibiotics. This is not only because of the issue of antimicrobial resistance but importantly about the effect of antibiotics on the gut microbiota. The digestive tract especially the large intestine is the habitat for millions of microbes living in concert with several functions of the body. Antibiotics have been very useful in treating and controlling infections with positive impact of standard of living.
Staphylococcus aureus is a frequent colonizer of human and several animal species, including dairy cows. It is the most common cause of intramammary infections in dairy cows. Its public health importance increase...
Nursing Open, EarlyView.
ConclusionsIn this study, the prevalence of Hr-TB among TB patients was higher than the prevalence of rifampicin resistance globally. Many patients with Hr-TB would be missed by current diagnostic algorithms driven by rifampicin testing, highlighting the need for new rapid molecular technologies to ensure access to appropriate treatment and care. The low prevalence of resistance to pyrazinamide and fluoroquinolones among patients with Hr-TB provides further justification for the recommended modified treatment regimen.
ConclusionOur findings argue against a co-selection mechanism of antimicrobial drug-resistance and zinc tolerance after dietary zinc supplementation in weaning piglets. An explanation for an increase in multi-drug resistant isolates from piglets with high zinc dietary feeding could be that resistant bacteria to antimicrobial agents are more persistent to stresses such as zinc or copper exposure.
This study sheds light on the virulence and AMR potential of E. coli ST302 strains and informs AMR genomic surveillance.
AbstractAn international legal agreement governing the global antimicrobial commons would represent the strongest commitment mechanism for achieving collective action on antimicrobial resistance (AMR). Since AMR has important similarities to climate change—both are common pool resource challenges that require massive, long-term political commitments—the first article in this spec ial issue draws lessons from various climate agreements that could be applicable for developing a grand bargain on AMR. We consider the similarities and differences between the Paris Climate Agreement and current govern...