Role of Interleukin-17 in Pathogenesis of Intestinal Fibrosis in Mice

ConclusionsIL-17 contributes to the pathogenesis of intestinal fibrosis, and anti-IL-17 therapy may weaken this effect by downregulating expression of profibrogenic cytokines and disturbing the MMP/TIMPs balance.
Source: Digestive Diseases and Sciences - Category: Gastroenterology Source Type: research