Medical News Today: Osteoporosis: Could selenium reduce risk?
A recent study concludes that consuming higher levels of dietary selenium shows an association with a reduced risk of developing osteoporosis.
Publication date: Available online 4 December 2019Source: Orthopaedics &Traumatology: Surgery &ResearchAuthor(s): Gilles Jean Marie Pasquier, Denis Huten, Harold Common, Henri Migaud, Sophie PutmanAbstractIntramedullary stem extensions will need to be extracted during total knee arthroplasty (TKA) revisions, especially repeated ones. These stems have various designs and lengths, can be straight or offset, cemented (partially or totally) or cementless, smooth or rough. This diversity adds to the difficult of extracting them, which the surgeon must anticipate before starting the revision procedure. Porous metaphyseal...
CONCLUSION: Osteoporotic BMD and osteoporotic fracture history were significantly, and independently, associated with an increased occurrence of echogenic plaques. Ultrasonographic screening of the carotid artery may benefit patients with osteoporosis. PMID: 31787146 [PubMed - in process]
CONCLUSIONS: The expression profile of lncRNAs was significantly altered in femur and quadriceps of OVX rat models, which may offer new insights into pathogenesis of osteoporosis and sarcopenia and potentially provide novel therapeutic targets. PMID: 31789293 [PubMed - in process]
We present a 16-year-old Chinese male patient with the typical features of APS, such as progeroid manifestations, cutaneous mottled hyperpigmentation, generalized lipodystrophy, and severe metabolic complications. The patient has also been detected with some rare and severe skeletal features, such as severe osteoporosis, generalized thinning of cortical bone, and recurrent femoral fractures. Genetic mutation detection in theLMNA gene revealed a de novo heterozygous mutation, the c. 29C>T (p. T10I).
Hui Chen, Xue-Jian Wu A new two-dimensional CoII-containing coordination polymer has been prepared using a light-harvesting triphenylamine type organic ligand, which could be applied for the degradation of organic dyes assisted by H2O2. In addition, the anti-osteoporosis activity of this complex has been studied both experimentally and computationally.
ConclusionsCompared to other pituitary adenomas, secreting and non-secreting, where pituitary surgery is the recommended first-line treatment, men with prolactinomas will usually respond to medical treatment with no need for any additional treatment.
EVENITY is a drug to treat osteoporosis (thinning and weakening of bone) in women after menopause ( “change of life”) who:• are at high risk of breaking a bone (fracture), or• cannot use another osteoporosis medicine or other osteoporosis medicines did not work well.
Contributors : Jichao Deng ; Zhanjun LiSeries Type : Expression profiling by high throughput sequencingOrganism : Oryctolagus cuniculusPRSS53, a member of the membrane-anchored serine proteases, hydrolyzes peptide bonds and is highly expressed in the hair follicle IRS, medulla, precortex and some melanocytes1. Previous studies reported that Prss53 is a psoriasis susceptibility locus and is linked to systemic lupus erythematosus, suggesting its potential roles in skin function2. The Q30R SNP in Prss53 may influence hair shape and is involved in the human variation of head hair shape among different continental groups1. In a...
To examine the correlation between dietary selenium (Se) intake and the prevalence of osteoporosis (OP) in the general middle-aged and older population in China.
AbstractSummaryThis first-in-human study of AGN1 LOEP demonstrated that this minimally-invasive treatment durably increased aBMD in femurs of osteoporotic postmenopausal women. AGN1 resorption was coupled with new bone formation by 12 weeks and that new bone was maintained for at least 5 –7 years resulting in substantially increased FEA-estimated femoral strength.IntroductionThis first-in-human study evaluated feasibility, safety, and in vivo response to treating proximal femurs of postmenopausal osteoporotic women with a minimally-invasive local osteo-enhancement procedure (LOEP) to inject a resorbable triphasic ost...