Single dose testosterone administration increases impulsivity in the intertemporal choice task among healthy males.

Single dose testosterone administration increases impulsivity in the intertemporal choice task among healthy males.
Horm Behav. 2019 Nov 22;:104634
Authors: Wu Y, Shen B, Liao J, Li Y, Zilioli S, Li H
Abstract
Circulating levels of testosterone have been positively associated with impulsivity. The present study investigates the effect of testosterone administration on impulsivity in an intertemporal choice task, where participants are given a choice between smaller-sooner rewards and larger-later rewards. Healthy young male participants (n = 111) received a single-dose of 150 mg testosterone gel in a double-blind, placebo-controlled, between-subjects design. At 180 min post-administration, participants performed the decision-making task. Both model-free (i.e., higher indifference point) and model-based (i.e., steeper discounting rate) parameters revealed that testosterone administration increased impulsive choice. This finding supports the hypothesis that exogenous testosterone increases impulsivity among healthy young males in a laboratory task.
PMID: 31765657 [PubMed - as supplied by publisher]

Source: Hormones and Behavior - November 21, 2019 Category: Endocrinology Authors: Wu Y, Shen B, Liao J, Li Y, Zilioli S, Li H Tags: Horm Behav Source Type: research