Increasing Clinical LC-MS/MS Assay Throughput Using a Full Calibration Curve Generated by One Injection from a Single-Tube Calibrator.

CONCLUSION: The results show that LC-MS/MS throughput can be increased by using a single-tube calibrator because it reduces assay calibration time while delivering equivalent results to those generated using traditional, multiple-tube calibrators. The single-tube calibrator may also offer cost savings to laboratories through reductions in consumable consumption, technician labor time, and inventory management, as well as to manufacturers because fewer vials would need to be manufactured, tested, stored, and shipped.
PMID: 31756771 [PubMed - as supplied by publisher]

Source: Rapid Communications in Mass Spectrometry : RCM - November 21, 2019 Category: Chemistry Authors: Cournoyer JJ, Dey S Tags: Rapid Commun Mass Spectrom Source Type: research