The PD-1 immune checkpoint promotes lung damage in murine models of COPD-like inflammation

Conclusion: Our data indicate that the activation of the PD-1 immune checkpoint contributes to lung damage induced by chronic COPD-like inflammation.

Source: European Respiratory Journal - November 20, 2019 Category: Respiratory Medicine Authors: Ritzmann, F., Vella, G., Lis, A., Angenendt, A., Herr, C., Bals, R., Beisswenger, C. Tags: Mechanisms of lung injury and repair Source Type: research