Manganese-Catalyzed Cascade Annulations of Alkyne-Tethered N-Alkoxyamides: Synthesis of Polycyclic Isoquinolin-1(2H)-ones

Org. Biomol. Chem., 2019, Accepted Manuscript DOI: 10.1039/C9OB02364J, CommunicationGui-Xian Kong, Jiao-Na Han, Dandan Yang, Jun-Long Niu, Mao-Ping Song A strategy for the synthesis of isoxazolidine/1,2-oxazinane-fused isoquinolin-1(2H)ones from alkyne-tethered N-alkoxyamides is described, in which cheap Mn(acac)2 is used as catalyst to facilitate a radical cascade annulation. The method features... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Organic and Biomolecular Chemistry - Category: Molecular Biology Authors: Source Type: research