Duration of type 2 diabetes and remission rates after bariatric surgery in Sweden 2007 –2015: A registry-based cohort study

The objective of the present study was to investigate the association between T2D duration and the chance of achieving remission of T2D after bariatric surgery. Methods and findingsWe conducted a nationwide register-based cohort study including all adult patients with T2D and BMI ≥ 35 kg/m2 who received primary bariatric surgery in Sweden between 2007 and 2015 identified through the Scandinavian Obesity Surgery Registry. The main outcome was remission of T2D, defined as being free from diabetes medication or as complete remission (HbA1c
Source: PLoS Medicine - Category: Internal Medicine Authors: Source Type: research

Related Links:

Nonalcoholic fatty liver disease (NAFLD) is tied to the rise in obesity and type 2 diabetes. Bariatric endoscopic interventions may provide an option to treat patients but there is scant data at present evaluating the effects on liver disease and diabetes.
Source: Surgery for Obesity and Related Diseases - Category: Surgery Authors: Source Type: research
ConclusionA high-level of suspicion is required to suspect, diagnose and treat post-RYGB complications. A bariatric on-call rota with appropriately trained personnel is essential.
Source: Obesity Surgery - Category: Surgery Source Type: research
Conclusionclinicians should be aware of such condition in patients with history of bariatric surgery who present with long-standing, intermittent abdominal pain.
Source: International Journal of Surgery Case Reports - Category: Surgery Source Type: research
Bianca Cox1†, Maria Tsamou1†, Karen Vrijens1, Kristof Y. Neven1, Ellen Winckelmans1, Theo M. de Kok2, Michelle Plusquin1 and Tim S. Nawrot1,3* 1Center for Environmental Sciences, Hasselt University, Hasselt, Belgium 2Department of Toxicogenomics, Maastricht University, Maastricht, Netherlands 3Department of Public Health, Environment and Health Unit, Leuven University (KU Leuven), Leuven, Belgium Maternal body mass index (BMI) before pregnancy is known to affect both fetal growth and later-life health of the newborn, yet the implicated molecular mechanisms remain largely unknown. As the master reg...
Source: Frontiers in Genetics - Category: Genetics & Stem Cells Source Type: research
Conclusion Taken together, evidence from animal and human studies demonstrates that the brain detects levels of circulating nutrients and hormones and consequently organizes an outward response that contributes to the regulation of whole-body glucose homeostasis. However, there are major knowledge gaps about the exact nature of this response and its relative importance compared to peripheral processes. As we have seen, animal studies have provided an anatomical map of CNS glucose regulation and have identified important neurons and neural circuits involved. Additionally, the CNS sensing of key nutrients and hormones has b...
Source: Frontiers in Physiology - Category: Physiology Source Type: research
Abstract BACKGROUND: Mechanisms of metabolic improvement after bariatric surgery remain incompletely understood. Intestinal glucose uptake is increased after gastric bypass in rodents, potentially contributing to reduced blood glucose and type 2 diabetes remission. OBJECTIVE: We assessed whether intestinal glucose uptake is increased in humans after gastric surgery. SETTING: University Hospital, United States. METHODS: In a retrospective, case-control cohort study, positron emission tomography-computerized tomography scans performed for clinical indications were analyzed to quantify intestinal gluco...
Source: Surgery for Obesity and Related Diseases : official journal of the American Society for Bariatric Surgery - Category: Surgery Authors: Tags: Surg Obes Relat Dis Source Type: research
Purpose Bariatric surgery is considered as an effective therapeutic strategy for weight loss in severe obesity. Remission of type 2 diabetes is often achieved after the surgery. We investigated whether increase in self-reported habitual physical activity associates with improved skeletal muscle insulin sensitivity and reduction of fat depots after bariatric surgery. Methods We assessed self-reported habitual physical activity using Baecke questionnaire in 18 diabetic and 28 nondiabetic patients with morbid obesity (median age, 46 yr; body mass index, 42.0 kg·m−2) before and 6 months after bariatric surger...
Source: Medicine and Science in Sports and Exercise - Category: Sports Medicine Tags: CLINICAL SCIENCES Source Type: research
This study describes the relationship between classic cardiovascular risk factors and inflammatory markers with BMI in a group of obese and non-obese subjects.Materials and MethodsObese subjects (BMI ≥ 30 kg/m2;n = 576; mean ± SD BMI 43.8 ± 7.58 kg/m2) scheduled for bariatric surgery were included. The reference population consisted of non-obese volunteers (BMI
Source: Obesity Surgery - Category: Surgery Source Type: research
The objective of this study was to investigate the effects of bariatric surgery on intestinal fatty acid (FA) uptake and blood flow. Materials and methodsWe recruited 27 morbidly obese subjects of which 10 had type 2 diabetes and 15 healthy age‐matched controls. Intestinal blood flow and fatty acid uptake from circulation were measured during fasting state using positron emission tomography (PET). Obese subjects were restudied six months after bariatric surgery. The mucosal location of intestinal FA retention was verified in insulin resistant mice with autoradiography. ResultsCompared to lean subjects, morbidly obese sub...
Source: Diabetes, Obesity and Metabolism - Category: Endocrinology Authors: Tags: ORIGINAL ARTICLE Source Type: research
CONCLUSIONS: It was demonstrated that a current mix of bariatric surgery methods was cost-effective at ten years post-surgery and cost-saving over the lifetime of the Belgian patient cohort considered in this analysis. PMID: 29271279 [PubMed - as supplied by publisher]
Source: Journal of Medical Economics - Category: Health Management Tags: J Med Econ Source Type: research
More News: Bariatric Surgery | Diabetes | Diabetes Type 2 | Eating Disorders & Weight Management | Endocrinology | Internal Medicine | Obesity | PET Scan | Study | Sweden Health