Cancers, Vol. 11, Pages 1825: MicroRNA-Mediated Metabolic Reprograming in Renal Cancer

In conclusion, we found that microRNAs upregulated in renal cancer contribute to disturbed expression of key genes involved in the regulation of RCC metabolome. miR-146a-5p and miR-155-5p emerge as a key “metabomiRs” that target genes of crucial metabolic pathways (PPP (the pentose phosphate pathway), TCA cycle, and arginine metabolism).

Source: Cancers - November 19, 2019 Category: Cancer & Oncology Authors: Bogus ławska Pop ławski Alseekh Koblowska Iwanicka-Nowicka Rybicka K ędzierska G łuchowska Hanusek Ta ński Fernie Piekie łko-Witkowska Tags: Article Source Type: research