Efficacy of a povidone iodine preparation in reducing nasal methicillin-resistant Staphylococcus aureus in colonized patients

Publication date: Available online 14 November 2019Source: American Journal of Infection ControlAuthor(s): Hussein Abou Ghaddara, Jessica A. Kumar, Jennifer L. Cadnum, Yilen K. Ng-Wong, Curtis J. DonskeyIn a randomized, nonblinded, placebo-controlled trial, a single application of a 10% povidone iodine preparation significantly reduced nasal methicillin-resistant Staphylococcus aureus at 1 and 6 hours after application, but suppression was not sustained at 12 or 24 hours. Twice-daily treatment for 5 days did not reduce nasal methicillin-resistant S aureus measured 12 hours postdosing in comparison to controls. These results suggest that single preoperative applications of povidone iodine will be effective for short-term suppression of S aureus during the perioperative period.
Source: American Journal of Infection Control - Category: Infectious Diseases Source Type: research