Pharmacokinetics and Safety of a Single Oral Dose of Peficitinib (ASP015K) in Japanese Subjects with Normal and Impaired Renal Function

ConclusionsPeficitinib exposure and TEAEs were similar in subjects with and without renal impairment after a single oral 150  mg dose. Based on these findings, it is not expected that peficitinib dose adjustment will be required in clinical practice, according to the degree of renal impairment.ClinicalTrials.gov identifierNCT02603497.
Source: Clinical Drug Investigation - Category: Drugs & Pharmacology Source Type: research