Genetic structure of natural populations of endangered Tor mahseer, Tor tor (Hamilton, 1822) inferred from two mitochondrial DNA markers
Publication date: Available online 14 November 2019Source: Meta GeneAuthor(s): Priyanka Sah, Sangeeta Mandal, Rajeev K. Singh, Raj Kumar, Abhinav Pathak, Nimisha Dutta, J.K. Srivastava, Ved Prakash Saini, Kuldeep K. Lal, Vindhya MohindraAbstractTor tor, Tor mahseer, an endangered cyprinid species, is important as sport fish. Genetic divergence in natural populations of T. tor was investigated using two mitochondrial genes, Cytb (Cytochrome b) and ATPase6/8. Analysis of 140 sequences of Cytb (1121 bp) and ATPase6/8genes (842 bp) genes revealed 12 and 7 haplotypes respectively, whereas 23 haplotypes were found in concatenated sequences (1963 bp). Sequence analysis of mitochondrial regions revealed balancing selection and displayed low nucleotide and moderate haplotype diversities. Mantel tests identified a positive relationship between pairwise geographical and genetic distances for the study region. Results of AMOVA based on genes pointed out that the genetic variations were mainly due to variation in within populations (ATPase6/8: 62.73%, Cytb: 42.13%, concatenated sequences: 48.31%). The total Fst was found to be significant in both genes with a value of 0.5787 (p
Authors: Karimi G, Vard B, Riyahi R, Motlagh ME, Heshmat R, Kelishadi R Abstract This cross-sectional study was conducted among 14,400 Iranian students, aged 7-18 years to determine the association between the frequency of family dinner and mental health. Family dinner frequency, family relationship, life satisfaction (LS), self-perceived health and anxiety were assessed by validated questionnaires. Of 14,274 participants, 50.6% were boys and 71.4% were urban residents, with a mean (SD) age of 12.28 (3.16) years. Family dinner frequency was significantly correlated with LS (boys: β = 0.27, p
In this study we explored the use of a natural compound rubusoside (RUB) as a solubilizer to enhance the solubility of a fluorescence-labeled C6-Ceramide (NBD C6-Ceramide) and to characterize its pharmacokinetics and tissue distribution in an animal model. RUB significantly enhanced the solubility of NBD C6-Ceramide by forming nanomicelles, and efficiently delivered NBD C6-Ceramide in rats by oral and intravenous administration. RUB loaded 1.96% of NBD C6-Ceramide in the nanomicelles and solubilized it to a concentration of 3.6 mg/mL in water. NBD C6-Ceramide in nanomicelles remained stable in aqueous solutions, all...
Publication date: Available online 10 December 2019Source: Prostaglandins &Other Lipid MediatorsAuthor(s): Giorgio Mottola, Evan Werlin, Bian Wu, Mian Chen, Anuran Chatterjee, Melinda Schaller, Michael S. ConteAbstractInflammation ensuing from vascular injury promotes intimal hyperplasia (IH) and restenosis. Resolvin D1 (RvD1) is a lipid mediator that attenuates IH in vivo when delivered locally to the vessel wall in animal models. We tested the hypothesis that peri-procedural oral administration of RvD1 could blunt the local inflammatory response to angioplasty, and attenuate downstream IH. Carotid angioplasty was per...
First-of-its-kind trial evaluates decision aid’s efficacy
Authors: Glauser W PMID: 31818934 [PubMed - in process]
Authors: Owens B PMID: 31818933 [PubMed - in process]
Authors: Dermer M, Martel J, Greenhill A PMID: 31818932 [PubMed - in process]
Authors: Robson R PMID: 31818931 [PubMed - in process]
Authors: Lamb S PMID: 31818930 [PubMed - in process]
Authors: Zimmer V, Glanemann M, Lammert F PMID: 31818929 [PubMed - in process]