New | phs000828.v1.p1 | Genomic Analysis of Hepatocellular Carcinoma

Genomic Analysis of Hepatocellular Carcinoma  (study page |release notes)
Source: dbGaP, the database of Genotypes and Phenotypes - Category: Genetics & Stem Cells Tags: StudyRelease Source Type: research

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Authors: Fan X, Chen G, Li Y, Shi Z, He L, Zhou D, Lin H Abstract Objective: Conflicting results existed about the role of prognostic nutritional index (PNI) for hepatocellular carcinoma (HCC) patients who received curative hepatectomy. The aim of this study is to identify the predictive capacity of PNI for survival after hepatectomy. Methods: Preoperative PNI, neutrophil-to-lymphocyte ratio (NLR), tumor feature and clinical information of 187 patients with HCC from Sir Run Run Shaw hospital were evaluated. We also conducted a meta-analysis of seven cohort studies. Results: Our study showed that HCC patients with a low PNI of
Source: Journal of Investigative Surgery - Category: Surgery Tags: J Invest Surg Source Type: research
Authors: Blann A Abstract In 2019 the British Journal of Biomedical Science published 40 articles in the various disciplines that comprise biomedical science. These were one review, 22 original articles and 17 'In Brief' short reports. Of those citing original data, the majority were in cellular pathology (14 papers), clinical chemistry (9 papers), and microbiology (6 papers: 4 in bacteriology and 2 in virology). There were 3 papers in haematology and 2 in andrology, whilst 5 papers crossed traditional discipline boundaries (such as the molecular genetics of IL6, liver function tests, and hepatocellular carcinoma)....
Source: British Journal of Biomedical Science - Category: Laboratory Medicine Tags: Br J Biomed Sci Source Type: research
Source: OncoTargets and Therapy - Category: Cancer & Oncology Tags: OncoTargets and Therapy Source Type: research
Publication date: Available online 11 December 2019Source: Clinica Chimica ActaAuthor(s): Haixia Yu, Ruixue Han, Jie Su, Hailong Chen, Dachao LiAbstractEarly diagnosis of Hepatocellular Carcinoma (HCC) is an important means to raise the survival rate of patients. Multi-marker combined detection is a powerful tool of early HCC diagnosis. Traditional detection methods are not effective and accurate because it is difficult to achieve combined detection of multiple markers. In this paper, we selected Alpha Fetoprotein (AFP) and miRNA-125b as the combined detection markers to improve the simultaneously diagnostic sensitivity an...
Source: Clinica Chimica Acta - Category: Laboratory Medicine Source Type: research
Source: Cancer Management and Research - Category: Cancer & Oncology Tags: Cancer Management and Research Source Type: research
Condition:   Hepatocellular Carcinoma Intervention:   Drug: CS3008 in combination with CS1001 Sponsor:   CStone Pharmaceuticals Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Hepatocellular Carcinoma Interventions:   Drug: CS1003+Lenvatinib;   Drug: CS1003 Placebo+Lenvatinib Sponsor:   CStone Pharmaceuticals Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Hepatocellular Carcinoma Intervention:   Drug: CS3008 in combination with CS1001 Sponsor:   CStone Pharmaceuticals Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Hepatocellular Carcinoma Interventions:   Drug: CS1003+Lenvatinib;   Drug: CS1003 Placebo+Lenvatinib Sponsor:   CStone Pharmaceuticals Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Authors: Lee YR, Park SY, Tak WY Abstract Background/Aims: The treatment outcomes and prognostic markers of acute variceal bleeding (AVB) in hepatocellular carcinoma (HCC) patients remain unclear. Therefore, we evaluated the clinical outcomes and prognostic factors of AVB in HCC patients. Methods: Cirrhotic patients with endoscopically confirmed AVB between 2007 and 2013 were enrolled in this prospective study. Prognostic factors were identified by multivariate Cox proportional hazards regression analysis. Results: Among the 329 enrolled patients, 125 patients (38.0%) were diagnosed with HCC. The 6-week mor...
Source: Gut and Liver - Category: Gastroenterology Tags: Gut Liver Source Type: research
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