Bilateral Limbus-Sparing Conjunctivitis in a Boy With Rash and Pneumonia

An adolescent boy presented with bilateral eye redness, an erythematous chest rash, lip blistering, and worsening sore throat for 2 days while receiving ciprofloxacin and trimethoprim-sulfamethoxazole for community-acquired pneumonia. Bedside ophthalmic examination revealed bilateral limbus-sparing conjunctival hyperemia that blanched minimally with phenylephrine, bilateral nasal and temporal conjunctival epithelial ulcerations, and inferior forniceal pseudomembranes. What would you do next?
Source: JAMA Ophthalmology - Category: Opthalmology Source Type: research

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Publication date: Available online 12 December 2019Source: Journal of Hospital InfectionAuthor(s): D.G. Wootton, S.J. Aston, T.W. Felton
Source: Journal of Hospital Infection - Category: Infectious Diseases Source Type: research
(CNN/CBS) — At least 1,300 people have died from the flu so far this season, according to a preliminary estimate released Friday by the US Centers for Disease Control and Prevention. There have been at least 2.6 million flu illnesses and 23,000 flu-related hospitalizations, according to the analysis. So far this season, the CDC has received reports of 10 children who have died from the flu, four more than the week before. Experts have warned that flu is hitting the United States early this year, and there are concerns that this early season could mean a particularly severe season overall. Flu spread significantly in ...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - Category: Consumer Health News Authors: Tags: Boston News Health Flu Source Type: news
ConclusionsIPAF seems to a distinct entity, with a low tendency to evolve in a definite CTD. Nevertheless, further studies are needed to better define the clinical evolution and the outcome of IPAF.
Source: Autoimmunity Reviews - Category: Allergy & Immunology Source Type: research
Conclusion: Astigmatism is associated with allergic conjunctivitis in children attending an urban school. PMID: 31827915 [PubMed]
Source: Journal of Ophthalmology - Category: Opthalmology Tags: J Ophthalmol Source Type: research
Conclusions: Our study suggests that endovascular recanalization for subacute to chronic symptomatic atherosclerotic BAO appears to be feasible in selected patients.
Source: Frontiers in Neurology - Category: Neurology Source Type: research
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Source: International Journal of Environmental Analytical Chemistry - Category: Chemistry Authors: Source Type: research
In this study, we used site-directed spin-labeling electron paramagnetic resonance spectroscopy to examine the interaction of ExoU with soluble analogs of phosphatidylinositol (4,5)-bisphosphate (PI(4,5)P2). We found that dioctanoyl PI(4,5)P2 binds to and induces conformational changes in a C-terminal four-helix bundle (4HB) domain of ExoU implicated previously in membrane binding. Other soluble phosphoinositides also interacted with the 4HB but less effectively. Molecular modeling and ligand docking studies indicated the potential for numerous hydrogen bond interactions within and between interhelical loops of the 4HB and...
Source: Journal of Biological Chemistry - Category: Chemistry Authors: Tags: Membrane Biology Source Type: research
ConclusionGraves disease is an uncommon trigger for the development of thrombotic thrombocytopenic purpura, and very few cases have been reported thus far. Therefore, clinicians should be aware of this association in the appropriate clinical context to comprehensively monitor hyperthyroid patients during treatment.
Source: Journal of Medical Case Reports - Category: General Medicine Source Type: research
Reena Goswami1, Gayatri Subramanian2, Liliya Silayeva1, Isabelle Newkirk1, Deborah Doctor1, Karan Chawla2, Saurabh Chattopadhyay2, Dhyan Chandra3, Nageswararao Chilukuri1 and Venkaiah Betapudi1,4* 1Neuroscience Branch, Research Division, United States Army Medical Research Institute of Chemical Defense, Aberdeen, MD, United States 2Department of Medical Microbiology and Immunology, University of Toledo College of Medicine and Life Sciences, Toledo, OH, United States 3Roswell Park Comprehensive Cancer Center, Buffalo, NY, United States 4Department of Physiology and Biophysics, Case Western Reserve University, Clev...
Source: Frontiers in Oncology - Category: Cancer & Oncology Source Type: research
LITFL: Life in the Fast Lane Medical Blog LITFL: Life in the Fast Lane Medical Blog - Emergency medicine and critical care medical education blog aka: Paediatric Perplexity 016 An 18 month old girl is brought in by Gran after developing a very red rash over the last 2 days. She was seen by her GP a few days before with fevers, sore throat and lethargy and was diagnosed as a viral infection. However the rash then came up the following day and she seemed to deteriorate… What is the diagnosis? + Reveal Answer expand(document.getElementById('ddet656783326'));expand(document.getElementById('ddetlink656783326')) S...
Source: Life in the Fast Lane - Category: Emergency Medicine Authors: Tags: Clinical Cases Pediatrics paediatric rash scarlet Source Type: blogs
More News: Bactrim | Cipro | Ciprofloxacin | Conjunctivitis | Opthalmology | Pneumonia | Sore Throat | Sulfamethoxazole | Trimethoprim